We are always looking for talented individuals to work with us!

Postdocs: postdoc@choderalab.org
Prospective graduate students: You can join the lab from any of these graduate programs:

OPEN POSITIONS

CHODERA LAB SEEKING AWESOME TECH TO HELP ADVANCE DRUG DISCOVERY SCIENCE WITH ROBOTS!

Research Tech Salary: $22.06-$33.18 hourly

What we’re looking for:

  • Life, physical sciences, or engineering BS/BA degree

  • Familiarity with Python and linux

  • Strong organizational skills (including within a wet lab setting; maintaining a lab notebook, inventory management/upkeep, etc.)

  • Interested in working with the Chodera Lab for at least two years

  • Most importantly, an unbounded enthusiasm for SCIENCE!

Other bonus (but not required!) experience:

  • Eagerness to learn about (or have previous experience with) laboratory robotics and automation

  • Basic knowledge of biochemistry and/or molecular biology

  • Interest in enzymatic assays

  • Knowledge of regression/curve fitting methods

  • Experience with bacterial protein expression, purification, and related molecular biology skills

  • Experience with electronic and hard-copy lab notebooks

What we're offering:

  • Highly competitive pay for research technicians ($22.06-$33.18 hourly; Yearly can range $41,900 – $62,900)

  • Working at the interface of automated experiments, machine learning, open-source software, and drug discovery within the Memorial Sloan Kettering Cancer Center / Tri-Institutional research campus in Manhattan

  • Networking opportunities with many of the pharma and biotech collaborators we work with

  • Training to help you move to the next phase of your career. Technicians in the lab have gone on to graduate programs (George Washington University), medical school (NYU Medical School), pharma (BioNTech), and biotech startups (Kingdom Supercultures).

Projects in the lab you'll be involved with:

  • Measure the impact of clinically identified mutations on clinical kinase-inhibitor binding, particularly focusing on identifying resistant mutations

  • Conduct high throughput assays measuring the impact of clinical kinase mutations on kinase activity

  • Collect systematic biophysical data on kinase-inhibitor binding in the context of clinical mutations to aid in the development of computational models and machine-learning tools

  • Lead a project collecting biophysical data to support the development of computational tools for predicting when cancer patients will respond to clinical kinase inhibitors

    • Design and execute machine learning and physics-based modeling projects to predict the impact of kinase mutations on inhibitor binding

  • Assess the accuracy of various probabilistic programming models compared to experimental data, train new models, identify datasets to collect, and design experiments to improve models

  • Drive new experimental approaches that include cell-free protein expression protocols and/or paper-based microfluidics to reduce the overall experiment time and cost

  • Assist in small infrastructure programming/maintenance projects (e.g. automation system dashboard)

Your main responsibilities in the lab would include:

  • Perform Lab Experiments (~50%): Assist ongoing research by conducting biophysical experiments for lab personnel and collaborators

  • Conduct Data Analysis/Reporting (~40%): Perform necessary analysis and calculations, record data, and write reports on research findings

  • Inventory Control/Quality Assurance (~5%): Help with the general upkeep of the wet lab

  • Additional Administrative Support (~5%): When our primary administrator is unable to assist

Location:

We’re looking to hire someone within the NYC area who will be able to easily commute into **Mortimer B. Zuckerman Research Center daily.**

How to apply:

Send an email to apply@choderalab.org with the following information:

  • Your contact information

  • A short note or cover letter describing why you’re interested

  • A current CV or resumé

You can also apply via the MSKCC Career portal (Requisition ID: 2024-76940), but please reference the Chodera Lab in your application and cover letter.

We’ll start contacting promising applicants immediately, but official offers will be made pending final approval of funding from MSKCC.